In Vitro Evaluation of Cytotoxicity and Anticancer Activity of Herbal Extract V2S2 (Coded Drug) on Human Cancer Cell Lines

Abstract Background Cancer is the leading cause of morbidity and mortality worldwide. It encompasses a large family diseases exhibiting abnormal cell growth with potential to invade or spread other part body. Natural extracts have been used as an efficient anticancer agent that show promising results. In this, study cytotoxicity effect Ayurvedic herbal extract code name V2S2 was studied compared control drug Adriamycin established chemotherapeutic drug. Materials Methods coded hydroalcoholic herbs. The in vitro performed sulforhodamine B assay TATA Memorial, ACTREC Mumbai per National Institute guidelines. Result GI50 on COLO-205, HOP-62, K-562, ISHIKAWA, HeLa, MCF-7, SCC-40, Hep-G2 MIA-PA-CA-2 less than 10 means both drugs equal activity. Conclusion group has more activity transient's standard Moreover, monkey kidney normal line shows same shown by Adriamycin.